Earnest Ross scored 15 points and Kenny Gabriel 14 for Auburn (7-10), which fell behind 22-3 in the first half and never got closer than 12 in the second. Former Shaw guard Chris Denson scored a career-high 12.
Guard Frankie Sullivan (knee) did not play for a third straight game and might not anytime soon. He remains eligible for a medical redshirt if he does not play another game this season.
Ravern Johnson scored 21 points and Renardo Sidney 15 for the Bulldogs (10-7, 2-1), who shot 62 percent.
Auburn is back in action Thursday, hosting Florida at 7 p.m. ET.